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Hemex: Sickle cell disease diagnosis

Sickle cell disease (SCD) is the most common genetic disease in the world. Every year, more than half a million babies are born with the disease. Without early diagnosis and access to basic care, mortality remains extremely high.

In 2025, we partnered with Hemex to provide a working capital facility (loan) to help the company scale up access to its Gazelle® SCD testing platform.

The challenge

Public health

SCD is a genetic condition that affects red blood cells, causing them to become stiff and crescent-shaped. These misshapen cells can block blood vessels, leading to pain, organ damage, and serious complications like anaemia, strokes and infections.

Without proper care, children with SCD face high risks – especially in low-resource settings. Around 500,000 babies are born with SCD each year, mostly in Sub-Saharan Africa and India. In 2021, sickle cell disease caused more than 81,000 deaths among children under five, making it the 12th leading cause of death in this age group worldwide. The true toll is likely even higher, as many children die before ever receiving a diagnosis.

Early diagnosis through newborn screening can save lives by enabling timely treatment – such as antibiotics, malaria prevention and vaccinations – and non-medical interventions. Despite its global impact, access to screening and care remains limited in many countries, making SCD a major public health concern recognised by the UN and WHO.

Market situation

In high-resource countries, newborn screening and proper care have greatly improved life expectancy for people with SCD. But in low-resource settings, scaling up testing and treatment is difficult, meaning millions of children are not tested and therefore those with SCD do not start treatment early.

Standard tests used in many countries rely on expensive equipment and skilled staff, which many low-resource areas cannot afford or support.

Near point-of-care (POC) testing, which takes place where the patient would be treated rather than in a laboratory, offers a more practical alternative, especially in remote regions. Hemex’s Gazelle® device is portable, accurate, and designed for use in these settings, helping make early diagnosis and care more accessible and affordable.

The product

The product

The Gazelle® diagnostic platform, launched in 2021, is a major innovation in sickle cell testing. It offers highly accurate, lab-quality results in minutes, using a simple, portable device that does not require expert training. 

It uses a small reader and disposable cartridges to analyse blood samples, delivering results in just eight minutes.

Gazelle® is accurate and easy to use in low-resource settings, and can also test for other conditions like malaria, hepatitis, and COVID-19. Clinical studies show it performs as well as standard lab tests.

 

 

The partnership

MedAccess has provided a $2.5 million working capital facility to Hemex.

Hemex will work to scale up access to its Gazelle® platform in India, the Middle East and sub-Saharan Africa.

Impact projections

SCD is a neglected area with limited global funding to support screening and early intervention. Hemex’s SCD test provides a near POC testing option that is easy to use and accurate.

The working capital facility will contribute to increased access to SCD testing through support for continued Hemex growth in India and across sub-Saharan Africa.

Lives changed

MedAccess projects that an additional six million people will be reached with SCD testing on the Gazelle® platform during the working capital facility’s three-year tenor.

Markets shaped

The working capital facility is expected to have significant market shaping impact on the sickle cell diagnostic market, and potentially impact the wider health system through increasing access to novel low-cost, accurate blood tests:

  • Accelerate scale-up
  • Encourage innovation and investment
  • Build competition.

How we calculate the impact of this agreement

Lives changed

People reached estimates are based on the public health context and expected usage rates of the Hemex Gazelle® platform.

Markets shaped

We work with partners, including donors, procurers and Ministries of Health, to track changes in health markets where our investments are supporting access to products. We monitor for changes to policy, procurement practices and supplier movement, all of which affect markets and contribute to the long-term sustainability of impact. 

 

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